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01 / The possibility

Biology is becoming programmable.

Explore the models, companies and technologies changing what we can build with biology.

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DIGITALBIO / FIELD NOTES01 — POSSIBILITY
SEQUENCE → STRUCTURE → POSSIBILITY
A new way to work with biologyIllustrative molecular schematic

02 / Understand

Big breakthroughs. Made understandable.

Start with the idea, not the jargon. DigitalBio connects the science to the questions that matter: what changed, what it enables, and where the limits are.

A concept, unpacked

What is protein structure prediction?

Sequence3D structure

A protein is a chain of amino acids. Its three-dimensional shape helps determine how it works. Structure prediction estimates that shape from the sequence.

A predicted shape is a hypothesis. It does not, by itself, prove that a protein works or that a drug will be effective.

Explore a real example: AlphaFold3 ↗Source: Abramson et al., Nature (2024) ↗

03 / Discover

Find the technology behind the breakthrough.

NextIn Bio turns a biological task into a starting point. Explore relevant Model Book records, then follow the evidence. A curated selection, never a claim to cover everything.

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04 / Compare

What’s possible is different from what’s practical.

A promising capability is only the beginning. Put the evidence, license and hardware requirements side by side before choosing what to evaluate.

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NextIn Bio / decision workspace

Model Book records. Different tests measure different things; scores are not a common ranking.
Decision lensAlphaFold3 ↗Google DeepMindBoltz-1 ↗MIT
CapabilitiesStructure Prediction · Complex Prediction · Ligand DockingStructure Prediction · Complex Prediction
Evidence

CASP15: 0.85 GDT-TS (avg)

CASP15: 0.82 GDT-TS (avg)

Licensingrestrictedopen
DeploymentAPI-only — no local deployment possible1x A100 40GB for most predictions
TradeoffsProduction drug discovery pipelines requiring IP freedomWhen absolute peak accuracy on complexes matters more than accessibility
Sources & reviewAlphaFold3 Paper (Nature 2024) ↗AlphaFold Server ↗CASP15 Results ↗Record reviewed Boltz-1 GitHub ↗Record reviewed
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05 / Share

Make better decisions together.

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06 / Build

Turn what you discover into something real.

Cells & Compute is where scientists, engineers and operators come together around real problems. Bring a question. Find a collaborator. Start building.

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Cells & Compute

Different disciplines.
Shared curiosity.

Science meets engineering meets the work of making it happen.

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Keep your curiosity close

The next idea starts here.

Accessible science, useful context, and a little room to think.